Scientific Associate Director PKDM (Small Molecule ADME) - CA

Company: Msccn
Location: South San Francisco
Posted on: April 1, 2026

Job Description:

ATTENTION MILITARY AFFILIATED JOB SEEKERS - Our organization works with partner companies to source qualified talent for their open roles. The following position is available to Veterans, Transitioning Military, National Guard and Reserve Members, Military Spouses, Wounded Warriors, and their Caregivers . If you have the required skill set, education requirements, and experience, please click the submit button and follow the next steps. Unless specifically stated otherwise, this role is "On-Site" at the location detailed in the job post. Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career. Scientific Associate Director - PKDM (Small Molecule ADME) What you will do Let’s do this. Let’s change the world. In this vital and exciting role you will oversee biotransformation activities and can serve as a project team representative focused on small molecule (SM) programs. You will characterize the absorption, distribution, metabolism, excretion (ADME) and pharmacokinetic (PK) properties of SM therapeutic drug candidates to achieve their full pharmacological potential. In this role, your core responsibilities include: Serving as a subject matter expert of small molecule biotransformation and leading biotransformation activities to support the programs and develop strategies to reduce/mitigate risks due to metabolism. Leveraging current biotransformation knowledge of metabolism as well as developing/implementing novel tools to efficiently support biotransformation related activities. Serving as a functional PKDM project team representative (PTR) and subject matter expert on the ADME/PK of small molecule therapeutics, collaborating with scientists across our PKDM scientific community Leveraging specialized ADME/PK skills such as in vitro ADME, in vivo ADME, biotransformation, PK/PD, or physiologically-based pharmacokinetic modeling (PBPK) to impact project progression and decision-making Planning and executing mechanistic ADME/PK analyses to integrate knowledge of drug design parameters, disease pharmacology, physiology, pharmacokinetics and pharmacodynamics to optimize dose selection and preclinical study designs. Contributing to the analysis of pre-clinical ADME and PK data for IND and NDA filings and documenting these analyses in appropriate reports Building close relationships with partner functions and therapeutic areas Additional Qualifications/Responsibilities What we expect of you We are all different, yet we all use our unique contributions to serve patients. The dynamic professional we seek is a subject matter expert with these qualifications. Basic Qualifications: Doctorate degree PhD OR PharmD OR MD [and relevant post-doc where applicable] and 4 years of directly related experience Or Master’s degree and 7 years of directly related experience Or Bachelor’s degree and 9 years of directly related experience Preferred Qualifications: PhD in Pharmacokinetics, Pharmaceutical Sciences, Engineering, or related fields with equivalent professional degrees and 10 years of experience in the Biotechnology/Pharmaceutical Industry, consulting or post-doctoral training Candidate should have solid technical experience with the application of SM in vitro/in vivo ADME and pharmacokinetics fundamentals to drug discovery projects Ability to drive the progression of SM discovery and development within project teams Establish SM biotransformation and ADME workflows for PKDM scientists. Expertise with in vitro ADME, in vivo ADME, PK/PD or PBPK Experience in supporting preclinical components of regulatory documentations. Excellent interpersonal, technical, and communication skills to lead cross-functional teams Past experience as a laboratory scientist in a pharma or biotech environment Excellent written and oral communication skills, attention to detail and accuracy, and interpersonal skills Record of scientific contributions through peer-reviewed articles and external presentations What you can expect of us As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we’ll support your journey every step of the way. The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications. In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include: A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan Stock-based long-term incentives Award-winning time-off plans Flexible work models, including remote and hybrid work arrangements, where possible Apply now and make a lasting impact with the Amgen team. careers.amgen.com In any materials you submit, you may redact or remove age-identifying information such as age, date of birth, or dates of school attendance or graduation. You will not be penalized for redacting or removing this information. Application deadline Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position. Pay Range by location South San Francisco: $216,073 - 255,336 Thousand Oaks: $202,013 - 227,352

Keywords: Msccn, Citrus Heights , Scientific Associate Director PKDM (Small Molecule ADME) - CA, Science, Research & Development , South San Francisco, California