In-vitro Scientist II
Location: South San Francisco
Posted on: June 23, 2025
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Job Description:
Duration: 6 months contract Description: The Quantitative,
Translational & ADME Sciences (QTAS) department is seeking a highly
motivated fulltime contract Scientist to join the In Vitro ADME
Sciences group (IVAS). The successful candidate will work in
collaboration with other team members to characterize the CYP
Induction properties of candidate drug molecules and may work on
other in vitro ADME assays. QTAS works very closely with other
disciplines (medicinal chemistry, pharmaceutical sciences,
pharmacology, toxicology etc.) to conduct preclinical studies,
support clinical evaluation and contribute to IND and NDA filings.
In this role, you will be a scientist with hands-on experience in
conducting in-vitro ADME assays including CYP450 induction assays
to characterize candidate drug molecules for potential to induce
CYP450 enzymes. Furthermore, you will provide support to project
teams to enhance mechanistic understanding of complex drug-drug
interactions. Core Job Responsibilities: Routinely conduct
(hands-on) evaluation of CYP450 induction Conduct qPCR assay
Interpretation of in vitro CYP induction data derived from assays
in human hepatocytes or reporter gene systems Perform human and
rodent hepatocytes cell culture, seeding and maintenance Perform
cell viability assessments and use microplate reader to measure
endpoints Contribute to the design of invitro ADME assays and data
interpretation Analyze data and maintain detailed, accurate and
comprehensible study documentations Use BioELN and GraphPad Prism
for data analysis Education and experience: BS (1-3 years relevant
experience) or MS in Biochemistry, Chemistry or Biology About US
Tech Solutions: US Tech Solutions is a global staff augmentation
firm providing a wide range of talent on-demand and total workforce
solutions. To know more about US Tech Solutions, please visit
www.ustechsolutions.com . US Tech Solutions is an Equal Opportunity
Employer. All qualified applicants will receive consideration for
employment without regard to race, color, religion, sex, sexual
orientation, gender identity, national origin, disability, or
status as a protected veteran. IND25
Keywords: , Citrus Heights , In-vitro Scientist II, Science, Research & Development , South San Francisco, California
